At the microscopic scale, temperature measurement technology faces unique challenges and opportunities, and the development of this field provides important support for nanotechnology, biomedical microscopic research, etc.
In the research of nanomaterials, temperature has a subtle impact on the physical and chemical properties of materials. Due to the extremely small size of nanomaterials, traditional temperature measurement methods are no longer applicable. New microscopic temperature measurement technologies have emerged, such as temperature measurement methods based on fluorescence spectroscopy. The fluorescence intensity or wavelength of certain fluorescent molecules changes with temperature. By labeling these fluorescent molecules on nanomaterials, the temperature at the nanoscale can be measured. This method has extremely high spatial resolution, which can be accurate to the nanometer level, providing a powerful tool for studying the thermal stability, phase change, and other behaviors of nanomaterials at different temperatures.
In the field of biomedical microscopic research, the measurement of intracellular temperature is crucial for understanding cellular physiological processes. Changes in intracellular temperature may be closely related to cell metabolism and disease occurrence. Using microscopic temperature measurement technology, such as nanothermometers, the temperature inside the cell can be measured. These nanothermometers usually have good biocompatibility and can accurately measure the temperature without affecting the normal function of the cell. For example, when studying the abnormal metabolism of cancer cells, by measuring the temperature change inside cancer cells, it can be found that the metabolic activity inside cancer cells is usually more active than that of normal cells, providing new ideas for the diagnosis and treatment of cancer.
Temperature measurement technology at the microscopic scale also has wide applications in micro - electro - mechanical systems (MEMS) and other fields. In MEMS devices, a small temperature change may affect the performance and reliability of the device. Accurate microscopic temperature measurement can help engineers optimize the design and manufacturing of MEMS devices to improve their performance and stability.
